Fantastic Four #1
The first appearance of Marvel’s first family, Mr Fastastic, Invisible Woman, Human Torch and The Thing. Also includes the 1st appearances of Mole Man and Tricephalous. The first family is coming to the MCU and the first movie will be directed by Jon Watts
Fantastic Four #2
1st appearance of the Skrulls, an shape shifting race that is an integral part of the Marvel universe. Seen in the MCU and coming in Secret Invasion TV series.
Fantastic Four #3
1st team appearance of the Fantastic Four in costume. 1st appearance of Miracle Man and the Fantastic car and helicopter.
Fantastic Four #4
1st appearance of anti hero Namor the Sub Mariner in the Marvel Universe, also included is first use of “Flame on” by the human torch.
Fantastic Four #5
1st appearance of Victor Von Doom aka Doctor Doom, the main adversary of the Fantastic Four.
Fantastic Four #6
First team of Namor and Doctor Doom against the Fantastic Four. 2nd appearance of both Namor and Doctor Doom!
Fantastic Four #12
The first battle of The Thing versus The Hulk. This spec issue has room to go up with the potential of a Hulk vs Thing in the MCU one day.
Fantastic Four #13
First appearance of Uatu The Watcher who sees all possible futures. Appearing in What if… on Disney plus.
Fantastic Four #18
The first appearance of the Super Skrull Kl’rt. His power include each aspect of the entire fantastic four team. 1st appearance of Emperor Dorrek. Look for this to be a spec book as well for the MCU!
Fantastic Four #19
1st appearance of Pharaoh Rama Tut who is later revealed as Kang The Conqueror who is now played by Jonathan Majors in the MCU.
Fantastic Four #22
2nd appearance of Mole Man but also the first time The Thing says his catch phrase. “It’s clobberin time”
Fantastic Four #45
First appearances of Black Bolt, Medusa, Lockjaw, Triton, Gorgon, Karnak and Crystal The Inhumans. A race of super humans created by the Kree.
Fantastic Four #46
First cover appearance of Black Bolt, 2nd appearance of the Inhumans.
Fantastic Four #48
1st appearance of Silver Surfer, 1st cameo of Galactus the world eater. Major implications for the MCU and spec books.
Fantastic Four #49
First appearance full appearance of Galactus, 1st cover appearance of Silver Surfer
Fantastic Four #52
1st appearance of T’Challa the Black Panther, leader of Wakanda. Played by the late Chadwick Boseman in the MCU.
Fantastic Four #62
1st appearance of Blastarr
Fantastic Four #65
1st appearance of Ronan the Accuser, judge, jury and executioner of the Kree people. Played by Lee Pace in the MCU. Also includes the first appearance of the Supreme intelligence.
Fantastic Four #66
Origin of HIM who later becomes Adam Warlock is will be played by Will Poulter in upcoming MCU projects.
Fantastic Four #94
1st appearance of Agatha Harkness played by Kathryn Hahn in the MCU. New show coming in the next couple years. Major implications for the MCU.
Fantastic Four Annual #6
1st appearance of Annihilus, ruler of the negative zone and possible future MCU major villain. Also includes the first appearance of Franklin Richards, son of Sue and Reed Richards.
Fantastic Four #185
1st appearance of Nicholas Scratch, a warlock and son of Agatha. A rabbit in Wandavision was named Scratch…speculation the rabbit could turn into something more in the upcoming show. 1st full appearance of the Witches of Salem.
Fantastic Four #211
1st appearance of Terrax The Tamer, a herald of Galactus. Possible book to spec on given the Fantastic Four implications for the MCU.
Fantastic Four #272
1st cameo of Nathaniel Richards, the father of Reed who exists in an alternate reality. He also turns out be Kang/Rama Tut.
Fantastic Four #273
1st full appearance of Nathaniel Richards, time traveller and Kang Prime. Major book to spec on
